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M9470099.TXT
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1994-07-02
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Document 0099
DOCN M9470099
TI Utility of paired blood cultures and smears in diagnosis of disseminated
Mycobacterium avium complex infections in AIDS patients.
DT 9409
AU Stone BL; Cohn DL; Kane MS; Hildred MV; Wilson ML; Reves RR; Denver
Disease Control Service, Denver Health and Hospital,; Colorado 80204.
SO J Clin Microbiol. 1994 Mar;32(3):841-2. Unique Identifier : AIDSLINE
MED/94253361
AB For 273 patients evaluated for disseminated Mycobacterium avium complex
infection, a total of 1,047 mycobacterial blood cultures (MBCs) were
submitted; the M. avium complex was recovered from 140 (13%) of the
specimens. Results for the paired MBCs were highly concordant: in 392 of
462 (85%) culture sets, both MBCs were negative, in 53 of 462 (11%)
sets, both MBCs were positive, and in only 17 of 462 (4%) sets was one
culture positive and the other negative. Acid-fast smears were done on
sediments from 671 specimens; smears were positive for 4 of 98 (4%)
cultures that grew the M. avium complex. A single MBC should be obtained
and then repeated if negative and disseminated M. avium complex
infection is still clinically suspected. Use of direct acid-fast smears
of sediments is not a reliable means of detecting mycobacteremia.
DE AIDS-Related Opportunistic Infections/COMPLICATIONS/*DIAGNOSIS/
MICROBIOLOGY Bacteremia/*COMPLICATIONS/*DIAGNOSIS/MICROBIOLOGY
*Bacteriological Techniques/ECONOMICS Costs and Cost Analysis
Diagnostic Errors Human Mycobacterium avium Complex/ISOLATION & PURIF
Mycobacterium avium-intracellulare Infection/*COMPLICATIONS/
*DIAGNOSIS/MICROBIOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).